A genetic map of mouse chromosome 12 composed of polymorphic DNA fragments.

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A genetic map of mouse chromosome 12 composed of polymorphic DNA fragments

Mouse chromosome 12 encodes the heavy chains of immunoglobulins (Igh), a family of T cell surface molecules, and a tumor antigen that may be homologous to immunoglobulins. To refine and extend the genetic map of this chromosome, a procedure has been developed to isolate chromosome 12-specific DNA fragments from a somatic cell hybrid carrying the chromosome on a Chinese hamster background. Five ...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1984

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.160.3.827